Restless legs syndrome (RLS) is a neurological sensorimotor disorder characterized by an overwhelming urge to move the legs in an effort to alleviate the effects of leg paresthesia.1 This common yet underdiagnosed condition results in sleep disturbance and chronic sleep deprivation that have a significant negative impact on daily activities and quality of life.1,2 The purpose of this Web site is to provide healthcare professionals with a better understanding of the etiology, epidemiology, and diagnostic criteria of RLS.